HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-1,2,4-Triazole → HCID 15433416, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(2,4-Difluorophenyl)-1,1-difluoro-1-(2-methoxyethyl)thio-2,3-epoxypropane | HCID 15434383 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 15433416 | HCID 15433416 | 12.4% |
Reaction Steps
Using 2-(2,4-difluorophenyl)-1,1-difluoro-1-(2-methoxyethyl)thio-2,3-epoxypropane (13.0 g, 0.044 mol), DMSO (100 ml), 1,2,4-triazole (7.6 g, 0.11 mol) and potassium carbonate (15.2 g, 0.11 mol), 2-(2,4-difluorophenyl)-1,1-difluoro-1-(2-methoxyethyl)thio-3-(1H-1,2,4-triazol-1-yl)propan-2-ol (2.0 g, yield: 12.0%) was obtained as colorless crystals by similar procedures to Example 14.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063945 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-e5971bada8ab4ad6944708806f2679b4 |
| Source note | uspto-grants-2000_05 |