4-(2-Methylimidazol-1-yl)benzyl chloride hydrochloride → 4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	4-(2-Methylimidazol-1-yl)benzyl chloride hydrochloride	HCID 18786342	—
Reactant	4-(3-Hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide	HCID 18786355	—
Product	4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide	HCID 11176798	—

Reaction Steps

4-(3-Hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide was reacted with 4-(2-methylimidazol-1-yl)benzyl chloride hydrochloride according to the procedure described in Example 2H to give the titled compound. mp: 183.0-186.0° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06063928
Source dataset	uspto-grants-2000_05
ORD ID	ord-fd289874f89946b2815becf91c90ec8b
Source note	uspto-grants-2000_05