反应详情

A suspension of 10.17 g (40.4 mM) of 1-(3-chlorobenzyl)-3-cyanoacetyl-urea in 80 ml of 2-propanol was added to a solution of 5.7 g KOH in 40 ml of 2-propanol and heated under reflux for 1 hour. After cooling the solid was collected and washed to give the crude title compound (9.07 g) as an off-white solid.

1. temperatureheated
2. temperatureunder reflux for 1 hour
3. temperatureAfter cooling the solid
4. customwas collected
5. washwashed