HCID 12050167, compound → HCID 12050168, compound

Participants

Reaction Steps

5.29 g of 3-cyclopropylmethyl-8-isopropyl-6-thioxanthine and 50 ml of propylamine were heated in a 450 ml reactor to 150° C. After 10 hours, the solution was evaporated to dryness, the residue dissolved in 200 ml of methanol, treated with 0.26 g of charcoal, filtered and concentrated. The crystals were collected, washed and dried to give the title compound (4.81 c) as off-white crystals mp 208-10° C.

Provenance & Evidence