N-bromobutanimide → HCID 54157086, compound

HRID 1108305Notes

Reaction equation

HRID 1108305 reaction equation
[CH3:1][N:2]([CH3:17])[S:3]([C:6]1[O:7][C:8]2[C:14]([O:15][CH3:16])=[CH:13][CH:12]=[CH:11][C:9]=2[CH:10]=1)(=[O:5])=[O:4].[Br:18]N1C(=O)CCC1=O>C(#N)C>[CH3:1][N:2]([CH3:17])[S:3]([C:6]1[O:7][C:8]2[C:14]([O:15][CH3:16])=[CH:13][CH:12]=[C:11]([Br:18])[C:9]=2[CH:10]=1)(=[O:5])=[O:4]

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 53728357HCID 53728357, compound

Product 1

HCID 54157086HCID 54157086, compoundYield 93.4%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared from 7-methoxybenzofuran-2-sulfonic acid dimethylamide (0.82 g) and N-bromosuccinimide (0.57 g) in acetonitrile (50 ml). Purification by column chromatography eluting with 50% ethyl acetate in hexane afforded the desired product as a pale yellow solid (1.0 g).

Workup

  1. customPurification by column chromatography
  2. washeluting with 50% ethyl acetate in hexane

Sources & evidence

ORD record
ord-c0d17a9715d141bda5e3114d1bd3d57c
Source dataset
uspto-grants-2000_05
Patent number
US06066657

Reaction notes

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