Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, compound

HRID 1108498Notes

Reaction equation

HRID 1108498 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Product 1

HCID 21925070HCID 21925070, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6 N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in next reaction.

Workup

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

Sources & evidence

ORD record
ord-f8ef375953254f27b60e8393ddd7a19e
Source dataset
uspto-grants-2000_05
Patent number
US06066730

Reaction notes

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