HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate | HCID 18783916 | — |
| Product | Trifluoroacetate | HCID 84468 | — |
| Product | 1-Methylpiperazin-2-one | HCID 4399042 | — |
Reaction Steps
1-tert-Butoxycabonyl-4-methyl-3-oxopiperazine (3.87 g) was dissolved in trifluoroacetic acid (80 ml), and the mixture stirred at ambient temperature for 2 hours. Solvent was evaporated to give 1-methyl-2-oxopiperazine as a trifluoroacetate salt, with some excess trifluoroacetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06069145 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-43b1a1cfe2f448ff8d6ddd42b1258618 |
| Source note | uspto-grants-2000_05 |