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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1108730Generated: October 30, 2026

Hydrochloric Acid → HCID 22627477, compound

https://huagongshe.com/reaction/1108730

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 22627245HCID 22627245—
SolventMethanolHCID 887—
SolventChloroformHCID 6212—
ProductHCID 22627477HCID 22627477—

Reaction Steps

To a solution of 3-isobutyryl-2-propyl-1-(2-pyridylmethyl)indole-6-carboxamide (80 mg) in chloroform (2 ml) was added 1M solution of hydrogen chloride in methanol (1 ml) at 25° C., and the mixture was stirred for 15 minutes. After evaporation of solvent, the residue was crystallized from a mixture of ethanol and ethyl acetate to give 3-isobutyryl-2-propyl-1-(2-pyridylmethyl)indole-6-carboxamide hydrochloride (80 mg) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06069156
Source datasetuspto-grants-2000_05
ORD IDord-37d1f843b886436c92a1215e46053fb7
Source noteuspto-grants-2000_05