4-(Trifluoromethyl)benzoyl chloride → HCID 19021184, compound

HRID 1108913Notes

Reaction equation

HRID 1108913 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1.[OH:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]2[N:26]=[CH:25][C:24]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])=[CH:23][N:22]=2)=[CH:17][CH:16]=1>N1C=CC=CC=1>[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7]([O:14][C:15]2[CH:16]=[CH:17][C:18]([C:21]3[N:22]=[CH:23][C:24]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])=[CH:25][N:26]=3)=[CH:19][CH:20]=2)=[O:8])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 676074-(Trifluoromethyl)benzoyl chlorideHCID 1358247454-(5-Nonyl-2-pyrimidinyl)phenol

Product 1

HCID 19021184HCID 19021184, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.01 m of p-(trifluoromethyl)-benzoyl chloride is added dropwise with stirring to a solution of 0.01 m of 2-p-hydroxyphenyl-5-nonylpyrimidine in 20 ml of pyridine at 0°-5°, the mixture is stirred for 20 hours at room temperature, and worked up as usual. p-(5-Nonylpyrimidin-2-yl)-phenyl p-(trifluoromethyl)-benzoate is obtained.

Sources & evidence

ORD record
ord-74c3ba9508f54063a3c831a0898fc7a7
Source dataset
uspto-grants-1994_06
Patent number
US05318721

Reaction notes

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