L-Aspartic Acid → HCID 25168487, compound

Participants

Reaction Steps

8.0 g (0.2 mol) sodium hydroxide and then 17.6 g (0.1 mol) cis-epoxysuccinic acid disodium salt were added with stirring at room temperature to 13.3 g (0.1 mol) L-aspartic acid in 50 ml water. The clear, pale yellow solution was heated under reflux for 8 hours. The solvent was then removed in a rotary evaporator (vacuum). 3-Hydroxy-2,2'-iminodisuccinic acid tetrasodium salt (B1) in the form of a C(3) epimer mixture was obtained in a yield of 36.8 g. According to 1H-NMR, the colorless solid contained approx. 5% by weight disodium tartrate (signal at=4.40).

Provenance & Evidence