反应详情

In a 50 ml-three-necked flask, 0.50 g (2.43 mM) of 2-amino-4-octylphenol, 0.82 g (2.54 mM) of 4-decyloxybenzoyl chloride and 20 ml of dioxane were placed and heated. To the mixture, 0.88 ml of pyridine was gradually added dropwise at around 90° C. under stirring, followed by further stirring for 35 minutes at around 90° C. After the reaction, the reaction mixture was poured into water to precipitate a crystal. The crystal was recovered by filtration and washed with water, followed by recrystallization from hydrous acetone to obtain 1.06 g of 2-(4-decyloxybenzoylamino)-4-octylphenol (yield: 90.4%).

1. temperatureheated
2. stirringby further stirring for 35 minutes at around 90° C
3. customAfter the reaction
4. customto precipitate a crystal
5. filtrationThe crystal was recovered by filtration
6. washwashed with water
7. customfollowed by recrystallization from hydrous acetone