反应详情

温度

170 °C

To a solution of 450 mg (1.5 mmol) of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-one in 10 ml of acetic anhydride was added 0.3 ml of conc. sulfuric acid and heated at 170° C. for 3 hours. The reaction mixture was evaporated under reduced pressure to give a residue, which was powdered with a ether/n-hexane mixture to give 505 mg of the objective crude compound as brown powder. This was employed for the subsequent reaction without purification.

1. customThe reaction mixture was evaporated under reduced pressure
2. customto give a residue, which