Sulfuric Acid → HCID 54159145, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 450 mg (1.5 mmol) of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-one in 10 ml of acetic anhydride was added 0.3 ml of conc. sulfuric acid and heated at 170° C. for 3 hours. The reaction mixture was evaporated under reduced pressure to give a residue, which was powdered with a ether/n-hexane mixture to give 505 mg of the objective crude compound as brown powder. This was employed for the subsequent reaction without purification.

Provenance & Evidence