Triphenylphosphine → HCID 19022088, compound

HRID 1109373Notes

Reaction equation

HRID 1109373 reaction equation
[Br:1][CH:2]1[CH2:6][CH2:5][N:4]([C:7](=[O:12])[NH:8][N:9]([CH3:11])[CH3:10])[C:3]1=[O:13].C1([P:20](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>>[Br-:1].[CH3:10][N:9]([CH3:11])[NH:8][C:7]([N:4]1[CH2:5][CH2:6][CH:2]([PH3+:20])[C:3]1=[O:13])=[O:12]

Participants

3

Reactant 2

HCID 11776TriphenylphosphineHCID 19022166HCID 19022166, compound

Product 1

HCID 19022088HCID 19022088, compound

Procedure

Substantially in the same manner as in Example 39 (2), 4.25 g (17 mmol) of the thus obtained 3-bromo-1-(N-dimethylaminocarbamoyl)-pyrrolidin-2-one and 4.46 g (17 mmol) of triphenylphosphine were treated to give 8.31 g of the objective crude compound as waxy residue.

Sources & evidence

ORD record
ord-398787aeb8334aa199fccd3968acb4d0
Source dataset
uspto-grants-1994_06
Patent number
US05319099

Reaction notes

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