反应详情

To 13 ml of methylene chloride, were dissolved 1.25 g of 4'-hydroxybiphenyl-4-carboxylic acid and 0.52 g of triethyl amine. To the solution was added 10 ml of methylene chloride solution of 1.2 g of nonanoyl chloride dropwise with stirring at an ambient temperature. Further, 0.2 g of dimethylamino pyridine was added and the solution was stirred for a whole day and night at an ambient temperature. After the termination of the reaction, the solution was concentrated under a reduced pressure, the reaction liquid was poured into water and neutralized, and the precipitate thus formed was separated by filtration, and washed with hexane, and dried under a reduced pressure to obtain 1.72 g of the desired compound.

1. stirringthe solution was stirred for a whole day and night at an ambient temperature
2. customAfter the termination of the reaction
3. concentrationthe solution was concentrated under a reduced pressure
4. customthe reaction liquid
5. customneutralized, and the precipitate thus formed
6. customwas separated by filtration
7. washwashed with hexane
8. customdried under a reduced pressure