Sodium Hydroxide → HCID 3720124, compound

Participants

Reaction Steps

By the method of Example 1, Step D, 40.0 g (0.12 mole) of 1-(2,4,6-trichlorophenyl)-4-ethoxycarbonyl-5-methyl-1H-pyrazole and 5.75 g (0.14 mole) of sodium hydroxide were reacted in 40 mL of ethanol and 30 mL of water, yielding 26.2 g of 1-(2,4,6-trichlorophenyl)-4-carboxy-5-methyl-1H-pyrazole as a light tan solid; mp 184°-186.5° C. The NMR spectrum was consistent with the proposed structure.

Provenance & Evidence