HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19020584, compound → HCID 19020581, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19020584 | HCID 19020584 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 19020581 | HCID 19020581 | — |
Reaction Steps
The 1-[2-chloro-4-(N-benzyloxycarbonyl-N-methylamino)benzoyl]-4-[2-(4-chlorophenyl)ethyl]-piperazine hydrochloride obtained in accordance with Example 18 is dissolved in 15 ml of methanol and debenzylated in the presence of 0.2 g of 10% palladium-on-carbon, yielding 1-[4-(N-methylamino)-2-chlorobenzoyl]-4-[2-(4-chlorophenyl)ethyl]-piperazine having a melting point of 200°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05321027 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-a6f6ffeca8064889a94c48b23ff41e52 |
| Source note | uspto-grants-1994_06 |