Hydrochloric Acid → HCID 13468123, compound

HRID 1109578Notes

Reaction equation

HRID 1109578 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([S:6][S:7][C:8]2[CH:12]=[CH:11][S:10][C:9]=2[C:13]([O-:15])=[O:14])=[C:2]1[C:16]([O:18]C)=[O:17].Cl>[OH-].[Na+].C(O)C>[S:1]1[CH:5]=[CH:4][C:3]([S:6][S:7][C:8]2[CH:12]=[CH:11][S:10][C:9]=2[C:13]([OH:15])=[O:14])=[C:2]1[C:16]([OH:18])=[O:17]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 86742084HCID 86742084, compound

Product 1

HCID 13468123HCID 13468123, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

aaa) 38.9 g of methyl 3,3'-dithiobis-thiophene-2-carboxylate were suspended in 1500 ml of 1N sodium hydroxide solution and 700 ml of ethanol, whereupon the suspension was heated under reflux until the reaction finished. After cooling, in an ice-bath the mixture was acidified with 25 percent hydrochloric acid, whereby the product crystallized out. By recrystallization from water, there was obtained 3,3'-dithio-bis-thiophene-2-carboxylic acid as colorless crystals of m.p. 256°-257°.

Workup

  1. temperatureunder reflux until the reaction
  2. temperatureAfter cooling, in an ice-bath the mixture
  3. customcrystallized out
  4. customBy recrystallization from water

Sources & evidence

ORD record
ord-b712356860254534a6db9059c446bee1
Source dataset
uspto-grants-1994_06
Patent number
US05321021

Reaction notes

Loading…