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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1109639Generated: October 28, 2026

Citric Acid → 2-Propanol, 1-methoxy-, 2-propanoate

https://huagongshe.com/reaction/1109639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantHydrochloric AcidHCID 313—
ReactantOxalic AcidHCID 971—
ReactantPhosphoric AcidHCID 1004—
ReactantSulfuric AcidHCID 1118—
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantMethanesulfonic AcidHCID 6395—
SolventAcetic AcidHCID 176—
SolventTolueneHCID 1140—
Product2-Propanol, 1-methoxy-, 2-propanoateHCID 11008049—

Reaction Steps

The catalysts used in the present invention include inorganic acids, such as sulfuric acid, hydrochloric acid and phosphoric acid, and organic acids, such as acetic acid, oxalic acid, citric acid, p-toluene sulfonic acid and methane sulfonic acid, among which the strong acids including sulfuric acid, p-toluene, sulfonic acid or methane sulfonic acid are preferred. Propylene glycol monomethyl ether propionate obtained according to the present application has a boiling point of 160.5° C., while other reactants and products having respective boiling point of 120° C. for PGM, 140.8° C. for propionic acid and 100° C. for water. It is apparently easier to rectify this solution comparing the respective boiling point of 146° C. for propylene glycol monomethyl ether acetate, 118° C. for acetic acid and 120° C. for PGM as in the conventional case. This is one of the effects achieved by the process according to the present invention.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05321152
Source datasetuspto-grants-1994_06
ORD IDord-abe7778d927a48e2908e51c27f7f7fc3
Source noteuspto-grants-1994_06