Propylamine → HCID 14749935, compound

HRID 1109737Notes

Reaction equation

HRID 1109737 reaction equation
[OH:1][CH2:2][C:3]1O[CH:5]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[C:7](=[O:9])[CH:8]=1.[CH2:29]([NH2:32])[CH2:30][CH3:31]>C(O)C.O>[OH:1][CH2:2][C:3]1[N:32]([CH2:29][CH2:30][CH3:31])[CH:5]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[C:7](=[O:9])[CH:8]=1

Participants

5

Reactant 2

HCID 7852PropylamineHCID 14749912HCID 14749912, compound

Product 1

HCID 14749935HCID 14749935, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A mixture of 20.0 g (51 mMole) 2-hydroxymethyl-5-octadecyloxy-4-pyranone and 30 mL of a 40% solution of propylamine in ethanol is heated in an autoclave at 100°-110° C. for 5 hours. After cooling, the crystallizate formed is taken up in water, stirred, filtered off, dried and recrystallized from ethyl acetate, colorless crystals thereby being obtained; m.p 120°-121° C.

Workup

  1. temperatureis heated in an autoclave at 100°-110° C. for 5 hours
  2. temperatureAfter cooling
  3. customthe crystallizate formed
  4. filtrationfiltered off
  5. customdried
  6. customrecrystallized from ethyl acetate, colorless crystals
  7. customthereby being obtained
  8. customm.p 120°-121° C.

Sources & evidence

ORD record
ord-bc925595a26f4d5289e6865c847933f0
Source dataset
uspto-grants-1994_06
Patent number
US05322844

Reaction notes

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