Pyridine → N-(5-bromo-3-((trimethylsilyl)ethynyl)pyrazin-2-yl)acetamide
Reaction equation
[Br:1][c:2]1[n:3][c:4]([C:9]#[C:10][Si:11]([CH3:12])([CH3:13])[CH3:14])[c:5]([NH2:8])[n:6][cH:7]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:21][C:22]([Cl:23])=[O:24].[cH:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1>>[Br:1][c:2]1[n:3][c:4]([C:9]#[C:10][Si:11]([CH3:12])([CH3:13])[CH3:14])[c:5]([NH:8][C:22]([CH3:21])=[O:24])[n:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-9b08032c03e1456b8a49ccdd9b57fa8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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