Sulfuric Acid → HCID 22075337, compound

Participants

Reaction Steps

24.9 g of ethyl 2-acetamido-3-oxo-3-phenylpropionate, 7.2 g of sulfuric acid (96%) and 50 ml of water are refluxed, with stirring, for 10 hours. The reaction mixture is filtered and the filtrate is concentrated on a rotary evaporator. The crystalline residue is made into a paste with 50 ml of isopropanol, the crystals are isolated by suction filtration, washed with petroleum ether (50°-70° C.) and dried.

Provenance & Evidence