Pyrrolidine → HCID 12493615, compound

HRID 1109916Notes

Reaction equation

HRID 1109916 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl[N:7]1[CH:12]=[C:11]([Cl:13])[CH2:10][N:9](Cl)[NH:8]1>>[Cl:13][C:11]1[C:12]([N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[N:7][N:8]=[N:9][C:10]=1[N:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 21613252HCID 21613252, compound

Product 1

HCID 12493615HCID 12493615, compound

Procedure

Pyrrolidine (28.5 g) is cooled on an ice bath. 1,3,5-Trichlorotriazine (18.4 g) is added with vigorous stirring. After -1.5 h the mixture is permitted to warm to 20°.25°. The solid is filtered and rinsed several times with water and dried under reduced pressure to give the monochloro-bis(1-pyrrolidinyl)triazine.

Workup

  1. waitAfter -1.5 h the mixture is permitted
  2. temperatureto warm to 20°
  3. custom25°
  4. filtrationThe solid is filtered
  5. washrinsed several times with water
  6. customdried under reduced pressure

Sources & evidence

ORD record
ord-7e50ccb6452a496d87bcf77dfe8c6e6b
Source dataset
uspto-grants-1994_06
Patent number
US05322943

Reaction notes

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