Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1110043Generated: November 2, 2026

Potassium Carbonate → HCID 15163161, compound

https://huagongshe.com/reaction/1110043

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1-IodohexaneHCID 12527—
Reactant2,3-Dihydrospiro(indene-1,4'-piperidine)HCID 15637616—
SolventDimethylformamideHCID 6228—
ProductHCID 15163161HCID 1516316152.6%

Reaction Steps

In the same way as that described in Example 1, step 5, the title compound was synthesised using spiro[indane-1,4'-piperidine] (0.4 g, 2.2 mmol), DMF (15 ml), potassium carbonate (0.33 g, 2.4 mmol) and iodohexane (0.62 g, 2.9 mmol). The crude residue was chromatographed in 1:1 petrol:ether to give 1'-hexylspiro[indane-1,4'-piperidine] (314 mg, 52%) as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05324733
Source datasetuspto-grants-1994_06
ORD IDord-b711090b63ee4a9ab4dd6471ffd324fd
Source noteuspto-grants-1994_06