HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 15163161, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Iodohexane | HCID 12527 | — |
| Reactant | 2,3-Dihydrospiro(indene-1,4'-piperidine) | HCID 15637616 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 15163161 | HCID 15163161 | 52.6% |
Reaction Steps
In the same way as that described in Example 1, step 5, the title compound was synthesised using spiro[indane-1,4'-piperidine] (0.4 g, 2.2 mmol), DMF (15 ml), potassium carbonate (0.33 g, 2.4 mmol) and iodohexane (0.62 g, 2.9 mmol). The crude residue was chromatographed in 1:1 petrol:ether to give 1'-hexylspiro[indane-1,4'-piperidine] (314 mg, 52%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05324733 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-b711090b63ee4a9ab4dd6471ffd324fd |
| Source note | uspto-grants-1994_06 |