HCID 18965399, compound → HCID 54487482, compound

HRID 1110066Notes

Reaction equation

HRID 1110066 reaction equation
C([O:8][C:9](=[O:33])[C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17]([C:19]2[CH:28]=[C:27]3[C:22]([C:23]([CH3:32])([CH3:31])[CH2:24][C:25]([CH3:30])([CH3:29])[O:26]3)=[CH:21][CH:20]=2)=[O:18])=[CH:12][CH:11]=1)C1C=CC=CC=1>C(OC(=O)C)C.[Pd]>[CH3:29][C:25]1([CH3:30])[CH2:24][C:23]([CH3:31])([CH3:32])[C:22]2[C:27](=[CH:28][C:19]([C:17]([O:16][C:13]3[CH:12]=[CH:11][C:10]([C:9]([OH:33])=[O:8])=[CH:15][CH:14]=3)=[O:18])=[CH:20][CH:21]=2)[O:26]1

Participants

4

Reactant 1

HCID 18965399HCID 18965399, compound

Product 1

HCID 54487482HCID 54487482, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

To a degassed solution of 400 mg (0.9 mmol) of Benzyl 4-(2,2,4,4-tetramethyl-7-chromanoyloxy) benzoate (Compound 2) in 15 ml of Ethylacetate, under argon was added 130 mg of 10% Palladium on carbon. The mixture was placed under a hydrogen atmosphere at 5 PSI and hydrogenated for 3 hours. The mixture was then filtered through celite and the filtrate was concentrated in-vacuo to give the title compound as a white solid.

Workup

  1. filtrationThe mixture was then filtered through celite
  2. concentrationthe filtrate was concentrated in-vacuo

Sources & evidence

ORD record
ord-646904ef88c7488884af7c3f52c22d1f
Source dataset
uspto-grants-1994_06
Patent number
US05324744

Reaction notes

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