反应详情

To a solution of 64 g (0.42 mole) 3-nitrobenzaldehyde in benzene was added 29.2 g of D-butylamine. The mixture was heated to reflux in a flask equipped with a Dean-Stark trap. After 90 minutes, the theoretical amount of water had separated, and the mixture was cooled and the solvent removed under vacuum, to give 84.4 g of N-(3-nitrobenzylidene)-1-butanamine.

1. temperatureThe mixture was heated
2. temperatureto reflux in a flask
3. customequipped with a Dean-Stark trap
4. customthe theoretical amount of water had separated
5. temperaturethe mixture was cooled
6. customthe solvent removed under vacuum