1-(1-Methylethoxy)-2-nitrobenzene → 2-(1-Methylethoxy)benzenamine

HRID 1110428노트

반응식

HRID 1110428 반응식
[CH3:1][CH:2]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N+:11]([O-])=O)[CH3:3].[H][H]>CO.[Ni]>[CH3:3][CH:2]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH2:11])[CH3:1]

참가 물질

5

반응물 2

HCID 1971801-(1-Methylethoxy)-2-nitrobenzeneHCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 344362-(1-Methylethoxy)benzenamine수율 94.4%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

1-(1-methylethoxy)-2-nitrobenzene, 45.26 g (0.25 mol) is dissolved in 500 ml of methanol, 4 g Raney nickel is added and the mixture is exposed to hydrogen gas until the required amount of hydrogen is absorbed. The methanol solution is filtered and concentrated in vacuo and the residue distilled to give 35.7 g (94.4%) of 2-(1-methylethoxy)benzenamine; bp 100-102 (at 4 mm).

후처리

  1. customis absorbed
  2. filtrationThe methanol solution is filtered
  3. concentrationconcentrated in vacuo
  4. distillationthe residue distilled

출처 및 근거

ORD 기록
ord-e14674bd76dd44d3a7e659f0c645e421
출처 데이터셋
uspto-grants-1990_12
특허 번호
US04975456

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