P-Toluenesulfonylhydrazide → HCID 70358998, compound

HRID 1110450Notes

Reaction equation

HRID 1110450 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=O)[CH2:7][CH2:6]2.[C:13]1([CH3:24])[CH:18]=[CH:17][C:16]([S:19]([NH:22][NH2:23])(=[O:21])=[O:20])=[CH:15][CH:14]=1>CCO>[S:19]([NH:22][N:23]=[C:8]1[C:9]2[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:11][CH:10]=2)[CH2:6][CH2:7]1)([C:16]1[CH:15]=[CH:14][C:13]([CH3:24])=[CH:18][CH:17]=1)(=[O:20])=[O:21]

Participants

4

Reactant 2

HCID 15303P-ToluenesulfonylhydrazideHCID 787875-Methoxyindan-1-one

Product 1

HCID 70358998HCID 70358998, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 5.00 g (31 mmol, Aldrich) of 5-methoxy-1-indanone and 6.33 g (34.0 mmol, Aldrich) of p-toluenesulfonhydrazide in 50 ml EtOH was heated on a steam bath until homogeneous. The solution was cooled and the solid which formed was filtered to yield 10.05 g (99%) of title compound as cream colored crystals: m.p. 195°-196° C.

Workup

  1. temperaturewas heated on a steam bath until homogeneous
  2. temperatureThe solution was cooled
  3. customthe solid which formed
  4. filtrationwas filtered

Sources & evidence

ORD record
ord-d11b12194c9e4a66916f01df58387df9
Source dataset
uspto-grants-1990_12
Patent number
US04975461

Reaction notes

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