1,4-Dioxane → 4-(4-{3-[1-(2,6-Dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-pyrazol-1-yl)-piperidine-1-sulfonic acid amide
Reaction equation
[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18](-[c:21]4[cH:22][n:23][n:24]([CH:26]5[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]5)[cH:25]4)[cH:19][c:20]23)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8].[NH2:32][S:33]([NH2:34])(=[O:35])=[O:36].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[c:12]2[cH:13][nH:14][c:15]3[n:16][cH:17][c:18](-[c:21]4[cH:22][n:23][n:24]([CH:26]5[CH2:27][CH2:28][N:29]([S:33]([NH2:32])(=[O:35])=[O:36])[CH2:30][CH2:31]5)[cH:25]4)[cH:19][c:20]23)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f4c9175475a544d89128df46b8eb3dc1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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