反应详情

As in Example 134, a solution of (E)-5,5-bis(3-nitrophenyl)-2,4-pentadienoic acid 4-nitrophenyl ester (0.950 g) and 3-pyridinebutanamine (0.34 g) in tetrahydrofuran (10 mL) was stirred at room temperature for 1 hour. The crude amide that had been isolated in the usual way, was crystallized from ethyl acetate-hexane to yield 0.82 g of (E)-5,5-bis(3-nitrophenyl)-N-[4-(3-pyridinyl)butyl)-2,4-pentadienamide mp 158°-159° C. Anal. Calculated for : C26H24N4O5 : C, 66.09; H, 5.12; N, 11.86 Found: C, 65.91; H, 5.34; N, 11.82.

1. customThe crude amide that had been isolated in the usual way
2. customwas crystallized from ethyl acetate-hexane