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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1110661Generated: November 4, 2026

2-Chloro-5-(trifluoromethyl)pyridine → 4-(3-Chloro-5-trifluoromethyl-2-pyridyloxy)phenoxypropionic acid chloride hydrochloride

https://huagongshe.com/reaction/1110661

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyridineHCID 92342—
Reactant2-(4-(5-Trifluoromethyl-2-pyridyloxy)phenoxy)propionic acid chloride hydrochlorideHCID 88451400—
Solvent2-Bromobutanoic acidHCID 6655—
Product4-(3-Chloro-5-trifluoromethyl-2-pyridyloxy)phenoxypropionic acid chloride hydrochlorideHCID 88451402—

Reaction Steps

By using 2-chloro-5-trifluoromethylpyridine instead of 2,3-dichloro-5-trifluoromethylpyridine in the above (b), 2-(4-(5-trifluoromethyl-2-pyridyloxy)phenoxy)propionic acid chloride hydrochloride was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04976773
Source datasetuspto-grants-1990_12
ORD IDord-91e77a33e58d41a2b34224f9a3bb40a5
Source noteuspto-grants-1990_12