Ethyl formate → HCID 14419056, compound

HRID 1110687Notes

Reaction equation

HRID 1110687 reaction equation
[CH3:1][C:2]1([CH3:11])[CH2:7][CH:6]([NH2:8])[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3]1.[CH:12](OCC)=[O:13]>>[CH:12]([NH:8][CH:6]1[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3][C:2]([CH3:11])([CH3:1])[CH2:7]1)=[O:13]

Participants

3

Reactant 2

HCID 8025Ethyl formateHCID 375244-Amino-2,2,6,6-tetramethylpiperidine

Product 1

HCID 14419056HCID 14419056, compound

Procedure

78 g of 2,2,6,6-tetramethyl-4-aminopiperidine in 250 ml of ethyl formate were refluxed for 10.5 hours. The precipitate which separated out was filtered off under suction, washed with a little petroleum ether and recrystallized from toluene. 4-(Formylamino)-2,2,6,6-tetramethylpiperidine was isolated as a colorless solid of melting point 153° C.

Workup

  1. customThe precipitate which separated out
  2. filtrationwas filtered off under suction
  3. washwashed with a little petroleum ether
  4. customrecrystallized from toluene

Sources & evidence

ORD record
ord-7229b32ed71d42f5b2fd6de5753532c6
Source dataset
uspto-grants-1990_12
Patent number
US04976889

Reaction notes

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