Triethylamine → HCID 14405647, compound

HRID 1110767Notes

Reaction equation

HRID 1110767 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][N:8]2[CH2:20][CH2:19][C:18]3[C:17]4[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=4)[NH:11][C:10]=3[CH2:9]2)[CH2:3][CH2:2]1.C(N(CC)CC)C.Cl[C:29]([O:31][CH2:32][CH3:33])=[O:30]>C(Cl)(Cl)Cl>[CH2:9]1[C:10]2[NH:11][C:12]3[C:17]([C:18]=2[CH2:19][CH2:20][N:8]1[CH2:7][CH:4]1[CH2:5][CH2:6][N:1]([C:29]([O:31][CH2:32][CH3:33])=[O:30])[CH2:2][CH2:3]1)=[CH:16][CH:15]=[CH:14][CH:13]=3

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 14405645HCID 14405645, compound

Product 1

HCID 14405647HCID 14405647, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

7.06 g (26.2 mmol) of 2-[(4-piperidyl)methyl]-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole, 70 ml of chloroform and 4 ml (26.2 mmol) of triethylamine are introduced under an argon atmosphere into a Keller flask, and 2.8 ml (26.2 mmol) of ethyl chloroformate are added.

Workup

  1. additionare added

Sources & evidence

ORD record
ord-c3ef3e07d20f43d1b7dca7c4bc9c1762
Source dataset
uspto-grants-1990_12
Patent number
US04977159

Reaction notes

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