Hydrochloric Acid → HCID 178507421, compound

HRID 1110911Notes

Reaction equation

HRID 1110911 reaction equation
[N+:1]([C:4]1[C:13]2[O:12][C:11]([C:14]3[NH:18][N:17]=[N:16][N:15]=3)=[CH:10][C:9](=[O:19])[C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-])=O.Cl>CO.[Pd]>[NH2:1][C:4]1[C:13]2[O:12][C:11]([C:14]3[NH:18][N:17]=[N:16][N:15]=3)=[CH:10][C:9](=[O:19])[C:8]=2[CH:7]=[CH:6][CH:5]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 178515803HCID 178515803, compound

Product 1

HCID 178507421HCID 178507421, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

1.59 g of the nitro compound obtained in Example 36, Step 3, above, is suspended in 46 ml of methanol to which 1 ml of concentrated hydrochloric acid, and 0.17 g of 5% palladium on carbon are added. The mixture is stirred under hydrogen at atmospheric pressure for 18 hours, filtered, and the filtrate concentrated in vacuo to 1.10 g 5-(8-amino-4-oxo-4H-1-benzopyran-2-yl)tetrazole.

Workup

  1. additionare added
  2. filtrationfiltered
  3. concentrationthe filtrate concentrated in vacuo to 1.10 g 5-(8-amino-4-oxo-4H-1-benzopyran-2-yl)tetrazole

Sources & evidence

ORD record
ord-afbbe2a96e094ea8bd8857b42d6fc614
Source dataset
uspto-grants-1990_12
Patent number
US04977162

Reaction notes

Loading…