HCID 19913878, compound → HCID 54198411, compound

HRID 1110918Notes

Reaction equation

HRID 1110918 reaction equation
[CH3:1][O:2][C:3](=[O:18])[CH2:4][C:5](=[O:17])[CH2:6][C:7]([C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][C:10]=1O)=[O:8]>Cl.CO>[CH3:15][C:12]1[CH:13]=[CH:14][C:9]2[C:7](=[O:8])[CH:6]=[C:5]([CH2:4][C:3]([O:2][CH3:1])=[O:18])[O:17][C:10]=2[CH:11]=1

Participants

4

Reactant 1

HCID 19913878HCID 19913878, compound

Product 1

HCID 54198411HCID 54198411, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolvent

Procedure

Methyl-5-(2-hydroxy-4-methylphenyl)-3,5-dioxopentanoate is dissolved in a saturated solution of hydrogen chloride in methanol and allowed to stand for 2 hours. The solution is evaporated and the crude product purified by flash chromatography on silica gel to give methyl 2-(7-methyl-4-oxo-4H-1-benzopyran-2-yl)acetate.

Workup

  1. customThe solution is evaporated
  2. customthe crude product purified by flash chromatography on silica gel

Sources & evidence

ORD record
ord-4c9f1cfd840246a88734cd0d258f0381
Source dataset
uspto-grants-1990_12
Patent number
US04977162

Reaction notes

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