Water → 2,3,4,5,6-Pentachlorobenzenemethanol

HRID 1110931Notes

Reaction equation

HRID 1110931 reaction equation
[Cl:1][C:2]1[C:7]([CH2:8]Br)=[C:6]([Cl:10])[C:5]([Cl:11])=[C:4]([Cl:12])[C:3]=1[Cl:13].[OH2:14]>CN(C=O)C>[Cl:1][C:2]1[C:7]([CH2:8][OH:14])=[C:6]([Cl:10])[C:5]([Cl:11])=[C:4]([Cl:12])[C:3]=1[Cl:13]

Participants

4

Reactant 2

HCID 962WaterHCID 15579165Pentachlorobenzyl bromide

Product 1

HCID 276412,3,4,5,6-Pentachlorobenzenemethanol

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 20.7 g of pentachlorobenzyl bromide in 300 ml DMF containing 30 ml of water was heated at reflux for two hours. On dilution with water solids precipitated. The solid was filtered out and washed on the filter until the wash water was free of bromide ions. On drying, 15.2 g of pentachlorobenzyl alcohol of m.p. 193°-195° C. were obtained.

Workup

  1. temperatureat reflux for two hours
  2. customOn dilution with water solids precipitated
  3. filtrationThe solid was filtered out
  4. washwashed on the
  5. filtrationfilter until the wash water
  6. customOn drying

Sources & evidence

ORD record
ord-84911aabf796405fa6c036bab8837b99
Source dataset
uspto-grants-1990_12
Patent number
US04977262

Reaction notes

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