Sodium Sulfide → 2-Amino-4-nitrobenzenethiol

HRID 1111084Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1111084
Cl[C:2]1[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:3]=1[NH2:4].[S-2:12].[Na+].[Na+]>C(O)C.O>[NH2:4][C:3]1[CH:5]=[C:6]([N+:9]([O-:11])=[O:10])[CH:7]=[CH:8][C:2]=1[SH:12]

Komponenten

4

Edukt 2

HCID 14804Sodium SulfideHCID 226912-Chloro-5-nitroaniline

Produkt 1

HCID 63364002-Amino-4-nitrobenzenethiol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 19096565Water ethanolLösungsmittel

Versuchsvorschrift

To a stirred solution of 172.6 g (1 mole) of 2-chloro-5-nitroaniline in boiling ethanol/water (5:2) is added a solution of sodium sulfide (generated from sodium sulfide nonahydrate and sodium bicarbonate), and the reaction is heated at reflux for one hour. The mixture then is cooled in ice, and the resulting crystalline product is collected by filtration and recrystallized from water.

Aufarbeitung

  1. temperaturethe reaction is heated
  2. temperatureat reflux for one hour
  3. temperatureThe mixture then is cooled in ice
  4. filtrationthe resulting crystalline product is collected by filtration
  5. customrecrystallized from water

Quellen und Nachweise

ORD-Eintrag
ord-aa4db449fea14b23bc26da906bd51aa2
Quelldatensatz
uspto-grants-1990_12
Patentnummer
US04978476

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