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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1111172Generated: October 30, 2026

1-Chloro-4-iodobutane → HCID 19003599, compound

https://huagongshe.com/reaction/1111172

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-iodobutaneHCID 82527—
ReactantLithiumHCID 3028194—
Reactant4-[(Pyridin-3-yl)methyl]benzonitrileHCID 14231168—
ProductHCID 19003599HCID 19003599—

Reaction Steps

Using procedure described in Example 36, the lithium salt of 4-(3-pyridylmethyl)-benzonitrile is treated with 1-chloro-4-iodobutane and the intermediate cyclized to obtain 1-(4-cyanophenyl)-1-(3-pyridyl)-cyclopentane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04978672
Source datasetuspto-grants-1990_12
ORD IDord-db05e254f0154d8a934a2f4425c3d1e4
Source noteuspto-grants-1990_12