Lithium iodide → HCID 15079804, compound

HRID 1111219Notes

Reaction equation

HRID 1111219 reaction equation
C([C:6]1[N:11]2[C:12]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:13]=3[C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[Cl:23])=[N:15][CH2:16][C:10]2=[N:9][C:8](=[O:29])[CH:7]=1)(OCC)=O.[I-].[Li+]>N1C=CC=CC=1>[Cl:28][C:25]1[CH:26]=[CH:27][C:12]2[N:11]3[CH:6]=[CH:7][C:8](=[O:29])[N:9]=[C:10]3[CH2:16][N:15]=[C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[Cl:23])[C:13]=2[CH:24]=1

Participants

4

Reactant 2

HCID 66321Lithium iodideHCID 15079786HCID 15079786, compound

Product 1

HCID 15079804HCID 15079804, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 32, 1-carboethoxy-9-chloro-7-(o-chlorophenyl)pyrimido[1,2-a][1,4]benzodiazepin-3(5H)-one was heated in pyridine with lithium iodide to give 9-chloro-7-(o-chlorophenyl)pyrimido[1,2-a][1,4]benzodiazepin-3(5H)-one.

Sources & evidence

ORD record
ord-a5db816614db4780993ae082dc92516d
Source dataset
uspto-grants-1990_12
Patent number
US04978753

Reaction notes

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