Lithium iodide → HCID 15079746, compound

HRID 1111220Notes

Reaction equation

HRID 1111220 reaction equation
C([C:5]1[N:10]2[C:11]3[CH:26]=[CH:25][C:24]([N+:27]([O-:29])=[O:28])=[CH:23][C:12]=3[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[Cl:22])=[N:14][CH2:15][C:9]2=[N:8][C:7](=[O:30])[CH:6]=1)(OC)=O.[I-].[Li+]>N1C=CC=CC=1>[N+:27]([C:24]1[CH:25]=[CH:26][C:11]2[N:10]3[CH:5]=[CH:6][C:7](=[O:30])[N:8]=[C:9]3[CH2:15][N:14]=[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[Cl:22])[C:12]=2[CH:23]=1)([O-:29])=[O:28]

Participants

4

Reactant 2

HCID 66321Lithium iodideHCID 15079787HCID 15079787, compound

Product 1

HCID 15079746HCID 15079746, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 32, 1-carbomethoxy-9-nitro-7-(o-chlorophenyl)pyrimido[1,2-a][1,4]benzodiazepin3(5H)-one was heated in pyridine with lithium iodide to give 9-nitro-7-(o-chlorophenyl)pyrimido[1,2-a][1,4]benzodiazepin-3(5H)-one.

Sources & evidence

ORD record
ord-66b07bf1c99b4cf991a044ac91c3dfae
Source dataset
uspto-grants-1990_12
Patent number
US04978753

Reaction notes

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