Ethanolamine → 4-(2,3-Dihydroxypropylamino)-3-nitrobenzonitrile

HRID 1111304Notes

Reaction equation

HRID 1111304 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[N+:13]([O-:15])=[O:14].NCC(O)[CH2:19][OH:20].C(CN)O>>[OH:1][CH:2]([CH2:19][OH:20])[CH2:3][NH:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[N+:13]([O-:15])=[O:14]

Participants

4

Reactant 3

HCID 700EthanolamineHCID 735613-Amino-1,2-propanediolHCID 15001944HC Yellow no. 14

Product 1

HCID 198289324-(2,3-Dihydroxypropylamino)-3-nitrobenzonitrile

Procedure

Preparation is similar to the synthesis in (a) above, except that 3-amino-1,2-propanediol is used in lieu of monoethanolamine.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-83fd9214df0c408dbcd81cf7bcffbf48
Source dataset
uspto-grants-1990_12
Patent number
US04980158

Reaction notes

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