11-Aminoundecanoic acid → Undecanoic acid, 11-(((2-benzoyl-4-chlorophenyl)sulfonyl)amino)-

HRID 1111345Notes

Reaction equation

HRID 1111345 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13].[C:15]([C:23]1[CH:28]=[C:27]([Cl:29])[CH:26]=[CH:25][C:24]=1[S:30](Cl)(=[O:32])=[O:31])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>[OH-].[Na+].C(Cl)Cl>[C:15]([C:23]1[CH:28]=[C:27]([Cl:29])[CH:26]=[CH:25][C:24]=1[S:30]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])(=[O:32])=[O:31])(=[O:22])[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

5

Reactant 2

HCID 1708311-Aminoundecanoic acidHCID 27566002-benzoyl-4-chloro-benzenesulfonyl Chloride

Product 1

HCID 3086745Undecanoic acid, 11-(((2-benzoyl-4-chlorophenyl)sulfonyl)amino)-

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 14798Sodium HydroxideSolvent

Procedure

24.16 g (0.12 mole) of 11-aminoundecanoic acid in 250 ml of normal caustic soda are added to 37.9 g (0.12 mole) of 2-benzoyl-4-chlorobenzenesulphonyl chloride in 250 ml of methylene chloride, at 0° C. and with stirring.

Sources & evidence

ORD record
ord-4505addb61684dd8afadb83d7b71bb05
Source dataset
uspto-grants-1990_12
Patent number
US04980349

Reaction notes

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