反应详情

7 ml of anhydrous triethylamine are added to 5.3 g of ethyl 11-aminoundecanoate hydrochloride in 30 ml of anhydrous methylene chloride and, after stirring for one hour at ambient temperature, 6.3 g of 2-benzoyl-4-chlorobenzenesulphonyl chloride are added dropwise. After stirring for 12 hours, the reaction medium is evaporated to dryness under vacuum, taken up with water and extracted with ethyl acetate. The organic phase which is washed with water until the washings are free of Cl- ions is dried over sodium sulphate and evaporated to dryness under vacuum.

1. stirringAfter stirring for 12 hours
2. customthe reaction medium is evaporated to dryness under vacuum
3. extractionextracted with ethyl acetate
4. washThe organic phase which is washed with water until the washings
5. dry with materialis dried over sodium sulphate
6. customevaporated to dryness under vacuum