Hydrochloric Acid → 4-(6-Chloro-pyrimidin-4-ylmethyl)-phenylamine

HRID 111149Notes

Reaction equation

HRID 111149 reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:14][c:15]1[cH:16][cH:17][c:18]([CH2:21][c:22]2[n:23][cH:24][n:25][c:26]([Cl:28])[cH:27]2)[cH:19][cH:20]1)([CH3:12])([CH3:13])[CH3:29].[Cl:30][CH2:31][Cl:32].[ClH:1].[O:2]1[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1>>[NH2:14][c:15]1[cH:16][cH:17][c:18]([CH2:21][c:22]2[n:23][cH:24][n:25][c:26]([Cl:28])[cH:27]2)[cH:19][cH:20]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 58659459Tert-butyl 4-((6-chloropyrimidin-4-yl)methyl)phenylcarbamate

Product 1

HCID 858915834-(6-Chloro-pyrimidin-4-ylmethyl)-phenylamine

Sources & evidence

ORD record
ord-5450c651709849ac9970cbb9d1c39ae7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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