Bromine → HCID 22152804, compound

Participants

Reaction Conditions

Reaction Steps

There is prepared in a first stage a solution of sodium hypobromite by adding, at 0° C., 3 cm3 of bromine to a stirred solution containing 7.5 g of soda in 35 cm3 of water. Then, there is slowly introduced a suspension of 1 g of 2-acetyl-6-ethylsulfonyl naphthalene dispersed in 20 cm3 of dioxan in a fashion to maintain the temperature of the reaction mixture lower than 5° C. At the end of the addition, this temperature is again maintained for 1 hour and then there are slowly added at ambient temperature 15 g of sodium metabisulfite dissolved in 150 cm3 of water. On acidifying the mixture with HCl, the anticipated acid precipitates. It is filtered, washed thoroughly with water and dried. 0.95 g of 6-ethylsulfonyl-2-naphthalene carboxylic acid in the form of a white powder whose melting point is 241° C. is obtained.

Provenance & Evidence