化工社化工社 化学情報印刷レポート · 研究参考用
Acetone → Methyl 3-amino-4-phenoxy-5-sulfamoylbenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | Methyl 3-nitro-4-phenoxy-5-sulfamoylbenzoate | HCID 53854447 | — |
| 触媒 | Nickel | HCID 935 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Methyl 3-amino-4-phenoxy-5-sulfamoylbenzoate | HCID 13020993 | — |
反応手順
35 g (~0.1 mol) of 3-nitro-4-phenoxy-5-sulphamylbenzoic acid methyl ester are suspended in 150 ml of methanol and are hydrogenated with Raney nickel (5-10%) in an autoclave at 40°-50° and 100 atmospheres gauge. The precipitated amino compound is dissolved by the addition of acetone on a steambath and the Raney nickel is removed by filtration.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04118397 |
| 出典データセット | uspto-grants-1978_10 |
| ORD ID | ord-eab54a3790a847a38e9f6b08e40e0fa8 |
| 出典メモ | uspto-grants-1978_10 |