Hydrochloric Acid → HCID 178433693, compound

HRID 1111673Notes

Reaction equation

HRID 1111673 reaction equation
[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][S:8][CH2:9][CH2:10][NH2:11].[C:12]([O-:17])(=[S:16])[C:13]([NH2:15])=[O:14].[K+].Cl>O>[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][S:8][CH2:9][CH2:10][NH:11][NH:15][C:13](=[O:14])[C:12]([OH:17])=[S:16]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 6655684-(((2-Aminoethyl)thio)methyl)-5-methylimidazoleHCID 23667932Potassium thiooxamate

Product 1

HCID 178433693HCID 178433693, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-(5-Methyl-4-imidazolylmethylthio)ethylamine is added to a solution of potassium thiooxamate in water. After 2 hours at room temperature the solution is acidified with hydrochloric acid to yield N-[2-(5-methyl-4-imidazolylmethylthio)-ethylamino] thiooxamic acid. This is then reacted with 2-(5-methyl-4-imidazolylmethylthio)ethylamine and trilead tetroxide according to the general procedure of Example 2 to yield N,N'-bis-[2-(5-methyl-4-imidazolylmethylthio)ethyl]amidinoformic acid.

Sources & evidence

ORD record
ord-9a74304172e54ff69fdea0e701fc8b87
Source dataset
uspto-grants-1978_10
Patent number
US04118502

Reaction notes

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