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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1111729Generated: November 2, 2026

Formaldehyde → 3-Morpholino-2-(2-pyrimidyl)propionitrile

https://huagongshe.com/reaction/1111729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantMorpholineHCID 8083—
Reactant(Pyrimidin-2-yl)acetonitrileHCID 15264944—
SolventMethanolHCID 887—
Product3-Morpholino-2-(2-pyrimidyl)propionitrileHCID 22767803—

Reaction Steps

The above prepared 2-(2-pyrimidyl)acetonitrile is reacted with formaldehyde and morpholine in methanol to give 3-morpholino-2-(2-pyrimidyl)propionitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04118567
Source datasetuspto-grants-1978_10
ORD IDord-a6d473b91d574987b5429fbe2f6a2ddb
Source noteuspto-grants-1978_10