Hydrochloric Acid → HCID 42001, compound

HRID 1111940Notes

Reaction equation

Cl.Cl.[NH2:3][C:4]1[C:9]([F:10])=[CH:8][C:7]([C:11](=[O:18])[CH2:12][NH:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[CH:6][C:5]=1[Br:19].[BH4-].[Na+]>>[NH2:3][C:4]1[C:9]([F:10])=[CH:8][C:7]([CH:11]([OH:18])[CH2:12][NH:13][C:14]([CH3:15])([CH3:17])[CH3:16])=[CH:6][C:5]=1[Br:19]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 4311764Sodium borohydride

HCID 22765875HCID 22765875, compound

Product 1

HCID 42001HCID 42001, compound

Procedure

m.p. of the hydrochloride: 207°-208° C. (decomp.), was prepared from 4'-amino-3'-bromo-2-tert.butylamino-5'-fluoroacetophenone hydrochloride and sodium borohydride analogous to Example 1.

Sources & evidence

ORD record: ord-7bcea648f5b141b3a2830f7bc66246ff
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

Loading…