Hydrochloric Acid → HCID 3041525, compound

HRID 1111958Notes

Reaction equation

Cl.[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([C:11](=[O:17])[CH2:12][NH:13][CH:14]([CH3:16])[CH3:15])=[CH:5][C:4]=1[Cl:18].[BH4-].[Na+]>>[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([CH:11]([OH:17])[CH2:12][NH:13][CH:14]([CH3:15])[CH3:16])=[CH:5][C:4]=1[Cl:18]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 4311764Sodium borohydride

HCID 13355789HCID 13355789, compound

Product 1

HCID 3041525HCID 3041525, compound

Procedure

m.p. of the hydrochloride: 185°-188° C., was prepared from 4'-amino-3'-chloro-5'-cyano-2-isopropylamino-acetophenone and sodium borohydride analogous to Example 2.

Sources & evidence

ORD record: ord-3ed7374274fb4d0b8a339e803faeab59
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

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